Nano/Bio Integrated System Laboratory
Faculty
Kan Shoji
- TEL:
- 0258-47-9767
Specialties
Mechanical Engineering/Fluid dynamics, Electrical Engineering/Robotics, Information Science/Intelligent mechanical Engineering, Chemistry/Analytical Chemistry
Research areas
1. Scanning Ion Conductance Microscopy using pore-forming proteins
2. Probe type nanopore sensors (Biological nanopore probe)
3. Bio sensors using microfluieic devices
4. Nanopore sensors using DNA nano structures
5. Environmental monitoring robots powered by insect biofule cells
Main facilities
Set up for Scanning Ion Conductance Microscopy (Scan range: 100 μm/each dimension, Resolution: z 0.1 nm, xy 0.2 nm)
NC milling system (MM100EX, Modia Systems)
Micropipette puller (P-1000, Sutter Instruments)
Patch-clamp amplifier (PICO2, Tecella)
Inverted microscope (Ts2, Nikon)
Syringe pump (YSP-202, YMC)
Gel electrophoresis
Forte of this laboratory's study
1. Formation of artificial cell membranes
2. Nanopore sensing with biological nanopores
3. Fabrication of microfluidic channels
4. Fabrication of micro electrodes and nano pipettes
5. Ion current measurements of transmembrane peptides and proteins
6. Biofuel cells
Achivements/proposals via industry-academia collabolations
Experiences
・Collaborated with Elwave Corp. about a micro wireless sensor that can be driven by a biofuel cell using insect hemolymph
Suggestion
・Automation and array system of lipid bilayer formation
・Applications of nanopore systems for drag discovery and diagnosis
Areas interesting to interact with
・Micro droplet manipulation
・Analytical Chemistry
・Nano positioning technologies
・Liquid biopsy
Intellectual properties
We are currently applying for a patent of a probe type nanopore sensor.
Message
Please contact us if you are interested in our techniques.
- Photograph of Microfluidic channel
- SEM images of Left) Gold nanoneedle electrode, Right) Glass-recessed micro silver electrode
- Wireless sensing robot using living insects
- Schematic illustration of nanopore sensing system using micro electrodes